NPC1L1 identified as a novel HCV entry factor
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منابع مشابه
Cyclophilin Inhibitors as a Novel HCV Therapy
A critical role of Cyclophilins, mostly Cyclophilin A (CyPA), in the replication of HCV is supported by a growing body of in vitro and in vivo evidence. CyPA probably interacts directly with nonstructural protein 5A to exert its effect, through its peptidyl-prolyl isomerase activity, on maintaining the proper structure and function of the HCV replicase. The major proline substrates are located ...
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ژورنال
عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology
سال: 2012
ISSN: 1759-5045,1759-5053
DOI: 10.1038/nrgastro.2012.4